nefazodone

n. a multifunctional antidepressant chemically related to trazodone but with some important pharmacological distinctions. It is an antagonist at 5-HT₂ serotonin receptors and an inhibitor of both serotonin and norepinephrine reuptake. This combination of actions is thought to be related to the lack of SSRI-like side effects associated with its antidepressant properties. Its sedative effects may be useful in the treatment of depression-related anxiety and insomnia; however, due to the risk of serious hepatic injury associated with nefazodone, it is now rarely used.

Browse dictionary by letter

a b c d e f g h i j k l m n o p q r s t u v w x y z

Psychology term of the day

May 9th 2024

gender differences

typical differences between men and women that are specific to a particular culture and influenced by its attitudes and practices. Gender differences emerge in a variety of domains, such as careers, communication, and interpersonal relationships. See also sex differences.