Proteus syndrome
a rare genetic disorder characterized by excessive and asymmetric growth of bones, skin, or organs. The overgrowth becomes evident in infants after about 6 months of age and progresses in severity with age. Neurological symptoms may be present, including intellectual disability, seizures, and vision loss. Proteus syndrome is caused by a random mutation in the AKT1 gene and is not inherited. Also called Wiedemann syndrome. See Elephant Man’s disease. [after the Greek god of the sea, Proteus, who could change his shape at will]