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n. 3,4-methylenedioxymethamphetamine: a substituted phenylethylamine that, like its analog MDA, is a catecholamine-like hallucinogen with amphetamine-like stimulant properties that may produce visual disturbances and hallucinations at high doses. It is among the most commonly used illicit drugs, generally sold under the name Ecstasy. Taken orally, onset of effects is rapid; the high lasts several hours, and residual effects can be experienced for several days. Intoxication is characterized by euphoria, feelings of closeness and spirituality, and diverse symptoms of autonomic arousal. Widespread illicit use of MDMA as a club drug has caused increasing concern as nerve damage and serotonin dysfunction have been established as resulting from prolonged use. Persistent memory dysfunction and impaired decision making and self-control as well as depressed mood have been well documented. When used during periods of intense activity (as often occurs during rave parties), it may be toxic or fatal. It may, however, have some beneficial clinical use and is being studied as a possible treatment for posttraumatic stress disorder.

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April 17th 2024