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Dutch Hunger Winter

during World War II, a Nazi-imposed famine in the Netherlands from October 1944 to May 1945, the effects of which were later associated with an increased risk of mental illness in the offspring born to Dutch women who were pregnant at the time. In particular, evidence from epidemiological studies of the Dutch Hunger Winter and of a similarly severe famine in China from 1959 to 1961 suggests that prenatal exposure to maternal starvation and nutritional deficiency plays a role in an offspring’s later development of schizophrenia. Also called Hunger Winter. See also fetal programming.

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Psychology term of the day

May 8th 2024

Down syndrome

Down syndrome

a chromosomal disorder characterized by an extra chromosome 21 and manifested by a round flat face and eyes that seem to slant (the disorder was formerly known as mongolism). Brain size and weight are below average; affected individuals usually have mild to severe intellectual disability and have been characterized as having docile, agreeable dispositions. Muscular movements tend to be slow, clumsy, and uncoordinated. In many cases, growth is stunted, the tongue is thick, and the fingers are stubby. Affected individuals may have heart defects and respiratory insufficiencies or anomalies that are often corrected during infancy by surgery. However, lifespan is reduced compared with that in the general population, and affected individuals typically show early onset of Alzheimer’s disease. Down syndrome is one of the most common physiological causes of intellectual disability. Also called Langdon Down’s disease; trisomy 21. See also autosomal trisomy of group G. [described in 1866 by John Langdon Haydon Down (1828–1896), British physician]