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alcohol dependence

in DSM–IV–TR, a pattern of repeated or compulsive use of alcohol despite significant behavioral, physiological, and psychosocial problems; it may also feature cravings, the development of tolerance, and characteristic withdrawal symptoms if use is suspended. The diagnosis is further differentiated from alcohol abuse by the preoccupation with obtaining alcohol or recovering from its effects. Alcohol dependence is sometimes considered to be the equivalent of alcoholism. In DSM–5, it and alcohol abuse have been subsumed into alcohol use disorder and are no longer considered distinct diagnoses. See also substance dependence

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Psychology term of the day

December 18th 2024

isoniazid

isoniazid

n. a drug of choice for the treatment of tuberculosis. Use of the drug can cause a form of neuritis by blocking the function of pyridoxine (vitamin B6) in metabolizing glutamic acid to form the neurotransmitter gamma-aminobutyric acid. Isoniazid is structurally related to a known monoamine oxidase inhibitor (MAOI), iproniazid, and was reputed to have some antidepressant activity, although it is not clinically used in this role and is not an MAOI. Also called isonicotinic acid hydrazide (INH).