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Zelen’s design

a type of randomized clinical trial in which patients are assigned to experimental conditions before they have consented to participate in the research. There are two versions of the design, both of which remain ethically controversial: In the single-consent strategy, patients assigned to the experimental treatment are told there is an alternative (the control) available and offered the option to switch; those in the control group are not informed of their study participation. In the double-consent strategy, both the experimental and control groups are offered the option to switch from the treatment to which they initially were assigned. [Marvin Zelen (1927–  ), U.S. biostatistician]

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Psychology term of the day

June 17th 2024

method of residues

method of residues

the fourth of the five canons of empirical science laid down by John Stuart Mill. It is meant to establish sufficient conditions for a phenomenon through the elimination of alternative potential causes on the basis of previous experiments or already known laws. For example, if the phenomena E1 and E2 occur together having antecedents C1 and C2, and if it is known by prior research or established law that C1 cannot cause E2 but causes E1, one may conclude that C2 is the cause of E2. Also called residue method.