Wolman’s disease
a genetic metabolic disorder characterized by a deficiency of acid lipase, an enzyme needed to break down lipid molecules. The adrenal glands become enlarged and calcified. Psychomotor development in affected infants appears delayed, and intellectual disability may be present but difficult to document because of overriding effects of vomiting, diarrhea, and other signs of acute illness. Also called primary familial xanthomatosis. [Moshe Wolman (1914–2009), Polish-born Israeli pathologist]