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Wernicke’s encephalopathy

a neurological disorder caused by a deficiency of vitamin B1 (thiamine). The principal symptoms are confusion, oculomotor abnormalities (gaze palsy and nystagmus), and ataxia. The disorder is most frequently associated with chronic alcoholism but is also found in cases of pernicious anemia, gastric cancer, and malnutrition. These symptoms are likely to resolve with thiamine treatment, although most individuals then develop severe retrograde and anterograde amnesia as well as impairment in other areas of cognitive functioning, including executive functions (see Korsakoff’s syndrome). Also called cerebral beriberi; Wernicke’s disease. [first described in 1881 by Karl Wernicke]

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Psychology term of the day

June 18th 2024

two-parameter model

two-parameter model

in item response theory, a model that specifies two parameters affecting an individual’s response to a particular test item: (a) the difficulty level of the item and (b) the item discriminability. See also Rasch model; three-parameter model.