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therapeutic window

the range of plasma levels of a drug within which optimal therapeutic effects occur. Suboptimal effects may occur both below and above the therapeutic window. Evidence for true therapeutic windows was never well established; perhaps the best evidence existed for the tricyclic antidepressant nortriptyline. Few modern psychotropic drugs require therapeutic monitoring, although lithium is a notable exception; it has a very narrow therapeutic range below which it has no therapeutic effect and above which adverse effects and toxicity dominate.

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Psychology term of the day

October 9th 2024

chromo- (chrom-; chromato-)

Sorry, "chromo-chrom-chromato" is not in the Dictionary of Psychology. Please report to APA if you believe this is an error.