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principle of nonmaleficence

in research ethics, the requirement of institutional review boards that studies “do no harm” to participants. When a person considers taking part in a study, there is an expectation that he or she will leave the study in a state that is no worse than when the study began. Where negative consequences are not entirely avoidable—as in an experiment in which a participant is required to recall painful memories, for example—researchers have a duty to minimize the impact of such consequences.

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