oculomotor nerve

the third cranial nerve, which contains both motor and sensory fibers and innervates most of the muscles associated with movement and accommodation of the eye and constriction of the pupil (i.e., all the muscles of the eye except the external rectus and superior oblique muscles). Also called cranial nerve III.

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Psychology term of the day

September 8th 2024

NMDA receptor

a type of glutamate receptor that binds NMDA as well as glutamate. NMDA receptors are coupled to ligand-gated ion channels and are also voltage-sensitive, which enables them to participate in a variety of information-processing operations at synapses where glutamate is the neurotransmitter. The drugs of abuse ketamine and PCP are antagonists at NMDA receptors, preventing the influx of calcium ions at calcium channels, which may cause the hallucinogenic effects of these drugs. Excessive flow of calcium ions into the presynaptic neuron via the NMDA receptor is thought to contribute to glutamate toxicity. A hypothesis on the etiology of schizophrenia involves dysfunction of the NMDA glutamate receptor (see glutamate hypothesis). Compare AMPA receptor.