mesoridazine

n. a conventional antipsychotic of the piperidine phenothiazine class. Mesoridazine is a low-potency agent that is a metabolic product of thioridazine. Like the latter drug, its use is associated with life-threatening disturbances in heart rhythm (prolongation of the Q-T interval potentially leading to torsades de pointes syndrome; see electrocardiographic effect). It should not be administered to individuals taking other drugs that prolong the Q-T interval or who have a history of heart rhythm disturbances, and it is appropriate for the treatment of schizophrenia only in individuals who have not responded to other antipsychotic agents. U.S. trade name: Serentil.

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Psychology term of the day

May 9th 2024

hierarchically nested design

any research design that involves several levels of sampling, such that the entities on the lower levels of the design are nested or subsumed within higher order groups. For example, a hierarchically nested design for an educational study might involve students (A), who are nested within classrooms (B), which are nested within schools (C), which are further nested within school districts (D). Several statistical procedures (e.g., analysis of variance, regression analysis, hierarchical linear models) also incorporate a hierarchical aspect. Also called hierarchical design; nested design.