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loxapine

n. an antipsychotic introduced into the U.S. market in the early 1970s. Loxapine differs from the conventional antipsychotics in that it binds strongly to serotonergic as well as dopaminergic receptors. Although its chemical structure (see dibenzoxazepine) is similar to that of the atypical antipsychotic clozapine, loxapine has the same antipsychotic, antiemetic, sedative, and extrapyramidal properties as the conventional antipsychotic agents. U.S. trade name: Loxitane.

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Psychology term of the day

February 25th 2025

single-case design

single-case design

an approach to the empirical study of a process that tracks a single unit (e.g., person, family, class, school, company) in depth over time. Specific types include the alternating treatments design, the multiple baseline design, the reversal design, and the withdrawal design. In other words, it is a within-subjects design with just one unit of analysis. For example, a researcher may use a single-case design for a small group of patients with a tic. After observing the patients and establishing the number of tics per hour, the researcher would then conduct an intervention and watch what happens over time, thus revealing the richness of any change. Such studies are useful for generating ideas for broader studies and for focusing on the microlevel concerns associated with a particular unit. However, data from these studies need to be evaluated carefully given the many potential threats to internal validity; there are also issues relating to the sampling of both the one unit and the process it undergoes. Also called N-of-1 design; N=1 design; single-participant design; single-subject (case) design.