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Leber’s disease

a hereditary visual disorder characterized by slowly progressive optic atrophy with normal peripheral vision but blind areas of the retina toward the center. The genetic defect is transmitted by females, but males are most often affected, with symptoms beginning around the third decade of life. Also called Leber’s optic atrophy. See also amaurosis. [Theodor Leber (1840–1917), German ophthalmologist]

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Psychology term of the day

May 8th 2024

sedative, hypnotic, and anxiolytic drug

sedative, hypnotic, and anxiolytic drug

any of a group of CNS depressants that have been developed for therapeutic use because of their calming effect (i.e., sedative) and ability to induce sleep (i.e., hypnotic) and reduce anxiety (i.e., anxiolytic). They include the barbiturates, meprobamate, and the benzodiazepines. At low doses, these drugs are prescribed for daytime use to reduce anxiety; at higher doses, many of the same drugs are prescribed as sleeping pills. Although efficacious when used sparingly, over the long term all induce marked tolerance, and cessation of use can precipitate potentially life-threatening withdrawal phenomena. Acute abuse can yield dangerous intoxication effects, and chronic abuse can cause a range of serious, irreversible conditions.