ketoconazole

n. an antifungal agent that has been suggested as a treatment for depression resistant to conventional drugs, due to its ability to inhibit the biosynthesis of steroids. No large-scale clinical data support this. Ketoconazole is a potent inhibitor of numerous cytochrome P450 enzymes (particularly CYP3A4) and has significant interactions with psychotropic drugs that utilize this metabolic path. Its numerous interactions and propensity to cause liver damage limit its use. U.S. trade name: Nizoral.

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Psychology term of the day

November 25th 2024

gynecology

n. the branch of medicine concerned with diseases and disorders of the reproductive organs of women. —gynecological adj. —gynecologist n.