ketoconazole

n. an antifungal agent that has been suggested as a treatment for depression resistant to conventional drugs, due to its ability to inhibit the biosynthesis of steroids. No large-scale clinical data support this. Ketoconazole is a potent inhibitor of numerous cytochrome P450 enzymes (particularly CYP3A4) and has significant interactions with psychotropic drugs that utilize this metabolic path. Its numerous interactions and propensity to cause liver damage limit its use. U.S. trade name: Nizoral.

Browse dictionary by letter

a b c d e f g h i j k l m n o p q r s t u v w x y z

Psychology term of the day

May 8th 2024

divergent thinking

creative thinking in which an individual solves a problem or reaches a decision using strategies that deviate from commonly used or previously taught strategies. This term is often used synonymously with lateral thinking. Compare convergent thinking. [defined in 1967 by Joy Paul Guilford]