the degree to which a research outcome cannot reasonably be attributed to the operation of chance or random factors. It is determined during significance testing and given by a critical p value, which is the probability of obtaining the observed data if the null hypothesis (i.e., of no significant relationship between variables) were true. Significance generally is a function of sample size—the larger the sample, the less likely it is that one’s findings will have occurred by chance. See also clinical significance; practical significance; significance level.