imipramine

n. a tricyclic antidepressant (TCA) with a tertiary amine molecular structure. It was originally synthesized in the hope of creating an effective antipsychotic but was observed to be ineffective in reducing psychotic symptoms. It did, however, seem to help individuals with severe depression and was subsequently marketed as an antidepressant. It is considered the prototype TCA, and like all tricyclic agents, its use as an antidepressant has been largely supplanted by less toxic drugs. It retains a therapeutic role as a sedative and adjunct in the management of neuromuscular or musculoskeletal pain. U.S. trade name: Tofranil.

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Psychology term of the day

January 30th 2025

analeptic

n. any stimulant other than amphetamines that produces subjective effects similar to those caused by amphetamine use. These effects may include alertness, elevated mood, increased energy, decreased appetite, irritability, and insomnia. The group includes diethylpropion, methylphenidate, and pemoline. See also appetite suppressant.