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GABAB receptor

one of the two main types of receptor protein that bind the neurotransmitter gamma-aminobutyric acid (GABA), the other being the GABAA receptorgabaa-receptor. GABAB receptors, which are G protein-coupled receptors, are less plentiful in the brain than GABAA receptors and do not have binding sites for benzodiazepine or barbiturate GABA agonists. Activation of GABAB receptors results in relatively long-lasting neuronal inhibition, but few psychotropic substances exert their effect at these receptors: Baclofen is a relatively selective agonist at GABAB receptors and is used clinically as a skeletal muscle relaxant.

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Psychology term of the day

May 8th 2024

alcoholic

alcoholic

n. a person who is dependent on alcohol, that is, who regularly drinks to the point of intoxication despite negative consequences. See also alcohol dependence.