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enzyme induction

the ability of drugs or other substances to increase the activity of enzymes, especially hepatic (liver) enzymes, that are responsible for the metabolism of those drugs or other substances. The cytochrome P450 hepatic enzymes, which are responsible for the metabolism of numerous psychotropic compounds, are susceptible to induction. Barbiturates, alcohol, benzodiazepines, some anticonvulsants, and steroids may induce hepatic enzymes, usually resulting in a decrease in activity of the drug or other substances metabolized via the same enzyme system. Substances contained in cigarette smoke, charbroiled meat, and environmental pollutants are also capable of enzyme induction.

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June 16th 2024