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chlordiazepoxide

n. the first commercially available benzodiazepine anxiolytic. Developed in 1957 and in clinical use in the early 1960s, it became one of the most heavily prescribed medications ever developed. It is characterized by extensive metabolism in the liver and possesses a number of metabolic products, giving it a lengthy half-life and a consequent long-acting anxiolytic effect. Its use in the management of anxiety and insomnia has been largely supplanted by benzodiazepines with less complicated metabolism and more predictable half-lives, but it remains in common use to protect against the effects of alcohol withdrawal. It is available in oral and injectable form. Because of erratic absorption, intramuscular administration is not advised. U.S. trade name: Librium.

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Psychology term of the day

January 31st 2025

protein metabolism

protein metabolism

all the biochemical reactions involved in the manufacture and breakdown of proteins. The body makes a large variety of complex proteins from amino acids, including enzymes, antibodies, certain hormones (e.g., insulin), and structural proteins, such as keratin, collagen, and the actin and myosin molecules of muscle. Proteins are broken down into their constituent amino acids during the basic turnover of cell proteins as well as for the elimination of toxic peptides and abnormal proteins. In case of severe energy starvation, with depletion of the body’s fat reserves, protein can be broken down to provide carbon to make glucose, but this impairs normal body functions.