acetaminophen
n. a common analgesic and antipyretic agent with an efficacy similar to aspirin, except that it does not possess antirheumatic or anti-inflammatory properties. It is rapidly distributed in the body and has a short half-life (around 2 hours). Acetaminophen is a widely used alternative to aspirin, especially when usage of the latter is inadvisable (e.g., in patients with bleeding disorders). It is also sold in combination with other analgesics, antihistamines, decongestants, or cough suppressants. However, acute overdose or chronic daily dosing of acetaminophen may cause liver damage (hepatotoxicity), and consumption of alcohol increases the risk of liver damage. Rapid intervention, including the administration of N-acetylcysteine, is required to prevent fatal hepatotoxicity after acetaminophen poisoning. Also called APAP; paracetamol. U.S. trade name (among others): Tylenol.