a disorder characterized by microcephaly, severe intellectual disability, obesity, seizures, hypogonadism, and distinct facial features. Fully expressed primarily in males, it is caused by an X-linked recessive trait mutation in the PHF6 gene. [Mats Gunnar Börjeson (1922– ), Hans Axel Forssman (1912–1994), and J. O. Orla Lehmann (1927– ), Swedish physicians]