n. an antidepressant, one of the secondary amine tricyclic antidepressants (TCAs), that inhibits the reuptake of norepinephrine and serotonin. It may also have antipsychotic activity. Amoxapine may cause extrapyramidal symptoms and tardive dyskinesia but is less associated with anticholinergic side effects than are other TCAs. U.S. trade name: Asendin.